To　realize　automatic　welding　flexible　wire,　a　micro-gripping　system　applied　in　handling　the　flexible　wires　with　a　diameter　of　tens　of　microns　was　designed　in　this　paper.　The　process　of　handling　the　flexible　wires　was　divided　into　four　sub-procedures,　i.e.,　the　position　computing,　the　wire-gripping,　the　wire-dragging　and　the　wire-releasing　sub-procedures,　which　were　realized　through　different　structures　and　methods.　The　position　computing　sub-procedure　output　the　relative　distance　between　the　micro-gripper　and　the　flexible　wire,　which　was　constructed　through　a　microscopic　stereovision　system.　The　other　three　sub-procedures　mainly　for　handling　the　flexible　wires　were　realized　through　designing　a　micro-gripper.　The　structure　of　the　micro-gripping　system　was　designed　and　composed　of　microscopic　the　stereovision　system,　the　micro-gripper　and　the　control　system.　Moreover,　the　mechanical　property　of　the　micro-gripper　was　simulated　precisely.　Results　show　that　our　system　can　precisely　compute　the　relative　distance　between　the　micro-gripper　and　the　wire,　and　effectively　grip,　drag　and　release　the　flexible　wires.　The　micro-gripping　system　can　be　widely　used　in　the　different　areas　of　micromanipulation.　©　2018,　Editorial　Department　of　Journal　of　Beijing　University　of　Technology.　All　right　reserved.