A　new　computational　methodology　is　proposed　for　fatigue　life　prediction　of　notched　components　subjected　to　variable　amplitude　multiaxial　loading.　In　the　proposed　methodology,　an　estimation　method　of　non-proportionality　factor　(F)　proposed　by　authors　in　the　case　of　constant　amplitude　multiaxial　loading　is　extended　and　applied　to　variable　amplitude　multiaxial　loading　by　using　Wang-Brown＇s　reversal　counting　approach.　The　pseudo　stress　correction　method　integrated　with　linear　elastic　finite　element　analysis　is　utilized　to　calculate　the　local　elastic-plastic　stress　and　strain　responses　at　the　notch　root.　For　whole　local　strain　history,　the　plane　with　weight-averaged　maximum　shear　strain　range　is　defined　as　the　critical　plane　in　this　study.　Based　on　the　defined　critical　plane,　a　multiaxial　fatigue　damage　model　combined　with　Miner＇s　linear　cumulative　damage　law　is　used　to　predict　fatigue　life.　The　experimentally　obtained　fatigue　data　for　7050-T7451　aluminium　alloy　notched　shaft　specimens　under　constant　and　variable　amplitude　multiaxial　loadings　are　used　to　verify　the　proposed　methodology　and　equivalent　strain-based　methodology.　The　results　show　that　the　proposed　methodology　is　superior　to　equivalent　strain-based　methodology.　Fatigue　life　prediction　method　is　proposed　for　notched　components　under　multiaxial　variable　amplitude　loading.　Pseudo　stress　correction　approach　by　FE　analysis　is　extended　to　determine　local　stress-　strain　increments.