• 综合
  • 标题
  • 关键词
  • 摘要
  • 学者
  • 期刊-刊名
  • 期刊-ISSN
  • 会议名称
搜索

作者:

Li, J.-Q. (Li, J.-Q..) (学者:李建强) | Zhang, L.-L. (Zhang, L.-L..) | Zhang, L. (Zhang, L..) | Yang, J.-J. (Yang, J.-J..) | Wang, Q. (Wang, Q..) (学者:王群)

收录:

Scopus PKU CSCD

摘要:

Objective To automatically extract the characteristics of fundus cataract by deep learning, construct a automatic classifier for cataract, and visualize the layer-by-layer feature transformation process of the intermediate layer of deep network. Methods Based on the clinical fundus image, a deep convolutional neural network (CNN) was used to directly learn useful features from the original representation of input data, and then the features extracted by the CNN were compared with pre-defined features. The deconvolution neural network (DN) method was used to quantitatively analyze the characteristics of each intermediate layer of CNN, analyze the pixel sets that have the most contribution to the prediction performance of CNN in the input image, and explore the process in characterizing cataract by CNN. Results The classifier constructed by deep learning achieved an average accuracy of 0.818 6 in four-category tasks. Compared with the existing predefined feature set, the feature set automatically extracted by the deep CNN performed better in representing characteristics of cataract. The features of the intermediate layer of CNN hierarchically transformed from low-level abstraction to high-level abstraction, including changed from gradient to edge, then to the combination of edge-like divergent structures, and finally to the high-level abstraction of blood vessel and optic disc information, and this transformation process coincided with the clinical diagnostic criteria of cataract. Conclusion The classifier based on deep learning is superior to the existing classifier in terms of performance. In addition, this method has potential application in detecting other eye diseases. © 2018, Second Military Medical University Press. All rights reserved.

关键词:

Artificial intelligence; Cataract; Deconvolution neural network; Deep convolutional neural network; Deep learning

作者机构:

  • [ 1 ] [Li, J.-Q.]School of Software Engineering, Beijing University of Technology, Beijing, 100124, China
  • [ 2 ] [Zhang, L.-L.]School of Software Engineering, Beijing University of Technology, Beijing, 100124, China
  • [ 3 ] [Zhang, L.]Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, China
  • [ 4 ] [Yang, J.-J.]Research Institute of Information Technology, Tsinghua University, Beijing, 100084, China
  • [ 5 ] [Wang, Q.]Research Institute of Information Technology, Tsinghua University, Beijing, 100084, China

通讯作者信息:

  • 李建强

    [Li, J.-Q.]School of Software Engineering, Beijing University of TechnologyChina

电子邮件地址:

查看成果更多字段

相关关键词:

相关文章:

来源 :

Academic Journal of Second Military Medical University

ISSN: 0258-879X

年份: 2018

期: 8

卷: 39

页码: 878-885

被引次数:

WoS核心集被引频次: 0

SCOPUS被引频次: 3

ESI高被引论文在榜: 0 展开所有

万方被引频次:

中文被引频次:

近30日浏览量: 4

在线人数/总访问数:205/2895314
地址:北京工业大学图书馆(北京市朝阳区平乐园100号 邮编:100124) 联系我们:010-67392185
版权所有:北京工业大学图书馆 站点建设与维护:北京爱琴海乐之技术有限公司