Finite　difference　method　was　used　to　analyze　the　distribution　of　shear　stress　and　shear　stress　gradient　at　the　surface　of　endothelial　cells　under　no-flow　conditions　and　exposed　to　steady　shear　stress　(12dyne/cm2,　24h).　The　results　showed:　under　no-flow　conditions,　the　maximum　shear　stress　was　1.8　times　of　average　shear　stress,　the　minimum　shear　stress,　almost　equate　to　zero;　under　flow　condition,　the　maximum　shear　stress　was　1.3　times　of　average　shear　stress,　the　minimum,　0.8　times.　The　shear　stress　and　shear　stress　gradient　distribution　depend　on　the　value　of　R(height/length).　The　shear　stress　is　almost　linearly　increased　with　R　increase.