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Due to difficulty in obtaining human cornea, pigs are often adopted as substitute models for cornea research because they are considered to have eyes similar to humans. The purpose of this study is to understand the similarities and difference in the biomechanical properties between human cornea and porcine cornea. 20 human cornea specimens and 30 porcine specimens were used for uniaxial test by Instron apparatus. Their tensile strength, stress-strain relationship, relaxation properties were tested. The tensile strength and stress-strain relation were very similar in the two kinds of specimens while significant differences were observed in the stress relaxation relationship: under the comparable stress and elongation level, porcine cornea relaxed much more significantly than human cornea. If tensile strength and stress-strain were the only mechanical factor to be investigated, porcine cornea could be used as a substitute model for human cornea research. However, when stress relaxation factors were concerned, the biomechanical properties were quite different in the two species. In conclusion, porcine cornea cannot be used as a model for human corneas in mechanical property studies.
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