Droplet　generation　in　a　T-shape　microchannel,　with　a　main　channel　width　of　50　,　side　channel　width　of　25　,　and　height　of　50　,　is　simulated　to　study　the　effects　of　the　forced　fluctuation　of　the　bottom　wall.　The　periodic　fluctuations　of　the　bottom　wall　are　applied　on　the　near　junction　part　of　the　main　channel　in　the　T-shape　microchannel.　Effects　of　bottom　wall＇s　shape,　fluctuation　periods,　and　amplitudes　on　the　droplet　generation　are　covered　in　the　research　of　this　protocol.　In　the　simulation,　the　average　size　is　affected　a　little　by　the　fluctuations,　but　significantly　by　the　fixed　shape　of　the　deformed　bottom　wall,　while　the　droplet　size　range　is　expanded　by　the　fluctuations　under　most　of　the　conditions.　Droplet　sizes　are　distributed　in　a　periodic　pattern　with　small　amplitude　along　the　relative　time　when　the　fluctuation　is　forced　on　the　bottom　wall　near　the　T-junction,　while　the　droplet　emerging　frequency　is　not　varied　by　the　fluctuation.　The　droplet　velocity　is　varied　by　the　bottom　wall　motion,　especially　under　the　shorter　period　and　the　larger　amplitude.　When　the　fluctuation　period　is　similar　to　the　droplet　emerging　period,　the　droplet　size　is　as　stable　as　the　non-fluctuation　case　after　a　development　stage　at　the　beginning　of　flow,　while　the　droplet　velocity　is　varied　by　the　moving　wall　with　the　scope　up　to　80%　of　the　average　velocity　under　the　conditions　of　this　investigation.