An　optofluidic　laser　based　on　a　hollow-core　negative-curvature　fiber　(HC-NCF)　is　proposed　and　demonstrated.　The　submicron-thick　circular　capillary　tubes　embedded　in　the　cladding　of　the　HC-NCF　act　as　antiresonant　elements　and　are　used　as　both　a　resonator　and　dye　microfluidic　channels.　A　stable　optofluidic　dye　laser　with　a　low　threshold　of　15.14　nJ/mm(2)　is　achieved.　The　laser　is　compact　and　robust　and　exhibits　directional　output.