Through　the　analysis　of　the　maximum　axial　stress　under　the　action　of　seismic　ground　motion　and　the　affecting　factors,　the　prediction　model　of　underground　pipeline　response　under　earthquakes　was　constructed　by　using　GRNN.　On　the　basis　of　the　model,　combining　the　orthogonal　array　with　the　theory　of　utility　function　and　ANN,　the　assessment　model　was　set　up　to　make　sensibility　analysis.　The　authors　made　a　comparison　between　the　results　obtained　from　the　traditional　limit　balance　analysis　and　the　results　from　the　proposed　method.　It　is　shown　that　the　results　from　the　proposed　method　are　valid　and　convenient.