To　consider　the　actual　fire　characteristics　in　the　fire　response　analysis　of　building　structures　and　to　simplify　the　complex　relationship　between　the　fire　analysis　model　and　the　structural　finite　element　analysis　model,　a　spatio-temporal　model　of　the　fire　temperature　and　heat　flux　boundary　for　heat　conduction　analysis　is　developed.　The　proposed　model　adopts　a　two-way　orthogonal　polynomial　approach　for　fitting　the　discrete　data　from　the　fire　simulation　and　obtains　continuous　spatial　polynomial　equations.　It　is　shown　to　be　accurate　for　capturing　the　distributions　of　temperature　and　heat　flux　that　are　required　for　a　heat　conduction　analysis　and　a　thermal　mechanical　coupling　analysis.　Finally,　the　model　is　implemented　through　user-subroutines　UTEMP　and　DFLUX　in　ABAQUS,　and　it　is　applied　to　a　new　archive　in　Beijing.　The　results　show　that　this　method　may　be　used　to　combine　fire　simulation　and　structural　analysis　for　the　safety　evaluation　of　structures　under　fire.