A　multi-cell　concrete-filled　still　tube(CFST)　mega-column　with　special　shaped　section　was　proposed,　and　its　seismic　behavior　under　horizontal　forces　in　different　direction　was　researched.　The　experimental　research　on　seismic　behavior　of　six　1/25　scaled　multi-cell　CFST　mega-column　models　was　carried　out　under　vertical　loading,　as　well　as　the　horizontal　low　cyclic　loading　in　different　direction.　The　axial　force　ratio　was　0.　5　and　0.　25.　The　horizontal　load　was　applied　along　the　long　axis,　the　short　axis,　and　in　the　direction　of　45°　intersetion　angle　with　long　and　short　axes,respectively.　The　load-bearing　capacity,　stiffness　and　its　degeneration,　ductility,　hysteretic　properties,　energy　dissipation　capacity,　and　failure　characteristic　of　models　were　analyzed　based　on　the　experimental　results.　Numerical　simulation　analysis　was　also　made,　and　the　its　results　agree　well　with　those　from　the　test.　The　results　show　that　the　multi-cell　CFST　mega-column　with　special　shaped　section　has　good　seismic　behavior,　and　the　behavior　is　relevant　to　the　direction　of　horizontal　forces　action.