This　paper　constructs　a　three-dimensional　model　to　numerically　investigate　the　heat　transfer　and　fluid　flow　characteristics　of　combined　microchannel　with　cone-shaped　micro　pin　fins　(MCPF)　for　inlet　Re　number　ranging　from　147　to　637.　Firstly,　the　cases　of　micro　pin　fins　located　in　the　upstream　(case1),　middle　(case2),　downstream　(case3)　of　microchannel　and　distributed　throughout　the　microchannel　(case4)　are　studied　with　fixed　number　of　fins.　Thereafter,　the　dimensionless　parameters　of　relative　fin　diameter,　relative　space　between　the　fins　and　relative　height　of　the　fin　are　studied　to　optimize　the　design.　The　variations　of　apparent　friction　factor　f(app),(ave)　and　average　Nusselt　number　Nu(ave)　with　inlet　Re　number　have　been　conducted,　and　the　thermal　enhancement　factor　(eta)　has　been　adopted　as　evaluation　criteria　to　determine　the　best　comprehensive　thermal-hydraulic　performance　of　MCPF.　The　results　show　that　the　microchannel　inserted　cone-shaped　micro　pin　fins　improves　the　heat　transfer　accompanied　with　a　higher　pressure　drop　as　compared　with　the　smooth　rectangular　(Rec)　microchannel.　Microchannel　with　uniform　fins　distribution　(case4)　has　the　largest　eta　and　the　bottom　wall　temperature　is　the　lowest　and　well-distributed　among　all　cases.　When　Re　＜　500,　the　overall　thermal　performance　of　case3　is　better　than　case1　but　when　Re　＞　500,　it　displays　a　contrary　tendency.　The　geometric　configuration　optimization　of　MCPF　suggests　that　there　is　an　optimum　pin　diameter,　fin　space　and　fin　height　that　satisfy　the　demands　of　heat　transfer　and　pressure　drop.