alpha-MnO2　nanotubes　and　their　supported　Au-Pd　alloy　nanocatalysts　were　prepared　using　hydrothermal　and　polyvinyl　alcohol-protected　reduction　methods,　respectively.　Their　catalytic　activity　for　the　oxidation　of　toluene/m-xylene,　acetone/ethyl　acetate,　acetone/m-xylene　and　ethyl　acetate/m-xylene　mixtures　was　evaluated.　It　was　found　that　the　interaction　between　Au-Pd　alloy　nanoparticles　and　alpha-MnO2　nanotubes　significantly　improved　the　reactivity　of　lattice　oxygen,　and　the　0.91　wt.%　Au0.48Pd/alpha-MnO2　nanotube　catalyst　outperformed　the　alpha-MnO2　nanotube　catalyst　in　the　oxidation　of　toluene,　m-xylene,　ethyl　acetate　and　acetone.　Over　the　0.91　wt.%　Au0.48Pd/alpha-MnO2　nanotube　catalyst,　(i)　toluene　oxidation　was　greatly　inhibited　in　the　toluene/m-xylene　mixture,　while　m-xylene　oxidation　was　not　influenced;　(ii)　acetone　and　ethyl　acetate　oxidation　suffered　a　minor　impact　in　the　acetone/ethyl　acetate　mixture;　and　(iii)　m-xylene　oxidation　was　enhanced　whereas　the　oxidation　of　the　oxygenated　VOCs　(volatile　organic　compounds)　was　suppressed　in　the　acetone/m-xylene　or　ethyl　acetate/m-xylene　mixtures.　The　competitive　adsorption　of　these　typical　VOCs　on　the　catalyst　surface　induced　an　inhibitive　effect　on　their　oxidation,　and　increasing　the　temperature　favored　the　oxidation　of　the　VOCs.　The　mixed　VOCs　could　be　completely　oxidized　into　CO2　and　H2O　below　320　degrees　C　at　a　space　velocity　of　40,000　mL/(g.hr).　The　0.91　wt.%　Au0.48Pd/alpha-MnO2　nanotube　catalyst　exhibited　high　catalytic　stability　as　well　as　good　tolerance　to　water　vapor　and　CO2　in　the　oxidation　of　the　VOC　mixtures.　Thus,　the　alpha-MnO2　nanotube-supported　noble　metal　alloy　catalysts　hold　promise　for　the　efficient　elimination　of　VOC　mixtures.　(C)　2017　The　Research　Center　for　Eco-Environmental　Sciences,　Chinese　Academy　of　Sciences.　Published　by　Elsevier　B.V.