Due　to　its　advantages　of　high　chemical　stability,　wind　energy　gap,　non-toxic　and　low　cost,　titanium　dioxide　exhibits　widely　promising　application　in　many　fields,　such　as　environmental　management,　new　renewable　energy　and　tissue　engineering.　It　has　been　believed　that　the　morphology　of　titanium　dioxide　plays　a　crucial　role　on　their　performance.　Among　different　morphologies,　titanium　dioxide　nanotube　(TNT)　fabricated　via　anodic　oxidation　method　has　a　highly　ordered　structure,　which　makes　titanium　dioxide　possess　numerous　application　in　dye　sensitized　solar　cell,　matrix　for　loading　novel　metal　catalysts　and　the　surface　modification　of　implant.　The　development　of　the　TNT＇s　preparation　and　application　in　dye　sensitized　solar　cell,　matrix　for　loading　novel　metal　catalysts　and　surface　modification　of　implant　is　summarized　in　the　present　paper.　The　future　development　of　TNT　is　outlooked　based　on　the　work　of　authors＇　group　and　other　literature　from　other　research　groups　all　over　the　world.　©　2016,　The　Editorial　Board　of　Materials　China.　All　right　reserved.