This　is　a　subsequent　study　of　a　two-lane　cellular　automata　(CA)　traffic　simulation　model　proposed　by　the　authors.　The　current　study　focused　on　understanding　the　impacts　of　the　configuration　of　the　differentiated　per-lane　speed　limit　(DPLSL)　and　its　compliance　rate　on　traffic　safety　indexes,　including　lane-changing　frequency,　the　coefficient　of　variation　of　speed,　and　incident　rate　of　dangerous　situations.　The　results　indicate　that　freeway　sections　with　DPLSL,　especially　the　ones　with　complex　DPLSL,　have　potentials　to　reduce　the　speed　variation,　lane　changing　frequencies,　and　chances　of　dangerous　situations,　resulting　in　higher　traffic　safety　levels.　Furthermore,　under　DPLSL　configurations,　the　compliance　rate　of　the　lane　of　slow　vehicles　could　positively　affect　the　traffic　safety　levels.　Specifically,　as　the　decrease　of　the　compliance　rate,　lane　changing　frequency　slightly　increases,　the　coefficient　variation　of　speed　especially　of　the　outer　lane　increases,　and　the　incident　rate　of　the　overtaking-on-the-right　circumstances　increases.　In　contrast　to　the　simple　DPLSL,　freeway　segments　with　the　complex　DPLSL　configuration　are　more　sensitive　to　the　influence　of　the　compliance　rate.