A　masonry　composite　structure　with　lightweight　concrete　filled　steel　tube　core　column　and　thermal-insulation　sandwich　is　proposed　in　this　paper.　In　order　to　research　the　seismic　performance　of　the　wall,　the　low-cycle　loading　experiments　on　three　different　composite　walls　combined　with　one　kind　of　technology　by　sliding　isolation　with　glass　bead　and　graphite　were　designed.　Specimen　one　was　lightweight　concrete　filled　steel　tube　core　column-regeneration　brick　wall,　specimen　two　was　lightweight　concrete　filled　steel　tube　core　column-flyash　blocks　interlayer-regeneration　brick　wall,　specimen　three　was　lightweight　concrete　filled　steel　tube　core　column-flyash　blocks　interlayer-adobe　wall　with　end　region　regeneration　brick.　The　failure　characteristics,　bearing　capacity,　ductility　and　hysteretic　behavior　were　analyzed.　In　addition,　the　formula　on　bearing　capacity　of　the　masonry　wall　with　lightweight　concrete　filled　steel　tube　core　column　and　thermal　insulation　interline　was　obtained.　Meanwhile,　the　calculated　results　coincide　well　with　the　experimental　ones.　The　researches　indicate　that　the　masonry　wall　with　lightweight　concrete　filled　steel　tube　core　column　and　thermal-insulation　sandwich　has　good　seismic　performance　and　it　can　be　applied　to　the　seismic　design　of　low-rise　masonry　structure.