A　kind　of　core-shell　hybrid　composite　(P@BMMs)　as　a　drug　carrier　was　prepared　through　seed　polymerization　method,　in　which,　biomodal　mesoporous　materials　(BMMs)　as　core　and　copolymer　poly(N-isopropylacryl-acrylamide)-co-poly(acrylicacid)　[P(NIPAM-co-AA)]　with　pH-and　temperature-responsive　characteristics　as　shell.　Its　structural　features　and　textural　parameters　were　characterized　using　various　techniques.　The　kinetic　and　thermodynamic　evaluation　demonstrated　the　existence　of　hydrogen　bond　interaction　between　IBU　and　P(NIPAM-co-AA)-coated　surfaces.　Meanwhile,　the　smart　thermo/pH-responsive　properties　of　ibuprofen　(IBU)　release　could　be　regulated　through　adjusting　coated　amount　of　copolymer.　Specially,　the　responsive　properties　of　P@BMMs　were　traced　by　small-angle　X-ray　scattering　technique,　suggesting　the　surface　roughness　and　structural　irregularities.