A　structure　with　CFST　columns　and　deep　steel　plate　beams　is　presented.　Four　specimens　were　tested　under　low　frequency　cyclic　loading.　The　four　specimens　with　the　same　aspect　ratio　are　constituted　by　CFST　columns　in　the　same　cross-section　and　deep　steel　plate　beams　of　the　same　size.　In　order　to　focus　on　the　seismic　performance　caused　by　the　deep　steel　plate　beams,　the　number　of　the　beams　is　different　for　deferent　specimens.　The　load-bearing　capacity,　stiffness　and　degradation　process,　ductility,　hysteretic　behavior,　energy　dissipation,　damage　and　failure　characteristics　of　specimens　were　discussed.　Based　on　the　experiment,　load-bearing　capacity　calculation　model　was　proposed　and　the　calculation　results　are　in　good　agreement　with　the　measured　results.　The　study　shows　that　the　structure　with　CFST　columns　and　deep　steel　plate　beams　has　good　seismic　performance.　In　order　to　achieve　the　ductile　yield　mechanism　of　strong　CFST　columns　and　weak　deep　steel　plate　beams,　the　design　parameters　of　deep　steel　plate　beams　will　be　matched　with　the　CFST　columns.　The　structure　with　CFST　columns　and　deep　steel　plate　beams　can　be　used　for　seismic　design　of　structures.　©,　2014,　Science　and　Technology　Periodical　Press.　All　right　reserved.