Objective:　To　analyze　and　compare　hemodynamic　features　of　two　different　options　for　modified　B-T　shunt　(MBTS)　surgery,　namely　end-to-side　(ETS)　and　side-to-side　(STS),　so　as　to　provide　references　for　clinical　treatment　of　single　ventricle　heart　defect　syndrome.　Methods:　The　real　geometric　model　was　reconstructed　by　medical　images　obtained　from　a　patient　with　hypoplastic　left　heart　syndrome　(HLHS);　MBTS　surgery　was　simulated　through　virtual　operations;　a　lumped　parameter　model　(LPM)　was　constructed　based　on　physiological　data　of　the　patient;　the　post-operational　boundary　conditions　of　computational　fluid　dynamics　(CFD)　models　(namely　STS　model　and　ETS　model)　were　predicted　based　on　the　LPM;　numerical　simulation　was　conducted　on　two　CFD　models　by　using　finite　volume　method.　Results:　Flow　details　and　wall　shear　stress　distributions　were　all　obtained　for　two　models.　The　mean　oscillatory　shear　index　(OSI)　of　ETS　model　and　STS　model　in　part　of　pulmonary　arteries　was　3.058×10-3　and　13.624×10-3,　respectively,　while　the　energy　loss　was　116.5　and　94.8　mW,　respectively,　and　blood　flow　rate　ratios　of　left　pulmonary　artery　to　right　pulmonary　artery　(RRPA/LPA)　were　0.8　and　1.72,　respectively.　Conclusions:　There　were　nearly　no　differences　between　two　CFD　models　in　energy　loss,　which　led　to　a　relatively　small　impact　on　the　surgery.　The　STS　model　had　a　more　balanced　pulmonary　artery　blood　perfusion　and　a　smaller　mean　OSI　in　part　of　pulmonary　arteries,　therefore,　the　STS　model　was　superior　to　the　ETS　model.　This　study　provides　an　important　theoretical　support　and　reference　for　treating　patients　with　HLHS.