China　has　experienced　serious　environmental　problems　along　with　rapid　economic　development　in　recent　years.　Industrial　production　is　the　fundamental　cause　of　Chinese　environmental　problems,　while　production　is　mainly　managed　and　governed　by　local　industrial　Parks.　Currently,　Chinese　industrial　parks　have　just　begun　to　think　about　sustainable　development,　and　the　demonstrative　parks　are　designated　as　eco-industrial　parks　(EIPs);　however,　the　EIPs＇　development　strategies　and　targets　are　still　vague　and　lack　scientific　guidance.　Therefore,　an　optimal　decision　making　approach　can　support　EIPs　to　address　environment　problems　and　achieve　regional　economic　development.　This　study　provides　an　integrated　approach　to　assess　the　multiple　impacts　of　EIP　development　strategies　and　propose　optimization　planning　by　using　a　case　study　in　Wuhu　EIP.　The　initially　constructed　decision-making　model　systemically　integrates　the　dynamic　model　of　the　Environment-Economic-Energy　(3Es)　system　and　an　input-output　model;　then,　the　model　is　established　and　simulated　using　a　linear　optimization　method.　An　optimal　development　strategy　can　be　put　forward　by　analysing　scenarios　for　the　Wuhu　EIP.　Based　on　the　findings　of　this　study,　there　are　several　substantial　opportunities　to　further　relieve　energy　pressure,　improve　the　environment,　and　support　socioeconomic　activities,　such　as　promotion　of　clean　production　and　subsidies　for　technological　improvements　and　changing　the　industrial　structure.　Additionally,　adopting　total　environmental　quantity　constraints　rather　than　intensity　constraints　is　an　urgent　need　in　EIP　planning.　This　study　provides　an　applicable　and　feasible　decision-making　basis　for　the　development　of　sustainable　industrial　parks.　(C)　2017　Elsevier　Ltd.　All　rights　reserved.