The　combination　of　topology　optimization　(TOP)　and　selective　laser　melting　(SLM)　provides　the　possibility　of　fabricating　the　complex,　lightweight　and　high　performance　geometries　overcoming　the　traditional　manufacturing　＂bottleneck＂.　This　paper　evaluates　the　biomechanical　properties　of　porous　structures　with　porosity　from　40%　to　80%　and　unit　cell　size　from　2　to　8　mm,　which　are　designed　by　TOP　and　manufactured　by　SLM.　During　manufacturability　exploration,　three　typical　structures　including　spiral　structure,　arched　bridge　structure　and　structures　with　thin　walls　and　small　holes　are　abstracted　and　investigated,　analyzing　their　manufacturing　limits　and　forming　reason.　The　property　tests　show　that　dynamic　elastic　modulus　and　compressive　strength　of　porous　structures　decreases　with　increases　of　porosity　(constant　unit　cell　size)　or　unit　cell　size　(constant　porosity).　Based　on　the　Gibson-Ashby　model,　three　failure　models　are　proposed　to　describe　their　compressive　behavior,　and　the　structural　parameter　lambda　is　used　to　evaluate　the　stability　of　the　porous　structure.　Finally,　a　numerical　model　for　the　correlation　between　porous　structural　parameters　(unit　cell　size　and　porosity)　and　elastic　modulus　is　established,　which　provides　a　theoretical　reference　for　matching　the　elastic　modulus　of　human　bones　from　different　age,　gender　and　skeletal　sites　during　innovative　medical　implant　design　and　manufacturing.