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作者:

Zhang, Z.-Z. (Zhang, Z.-Z..) (学者:张忠占) | Qiao, A.-K. (Qiao, A.-K..) (学者:乔爱科) | Fu, W.-Y. (Fu, W.-Y..)

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摘要:

Objective: To investigate the hemodynamic effect of stents with different types of links on treating vertebral artery stenosis, and provide scientific guidelines for the design of stent structure and the clinical procedure of stent intervention. Methods: Models of vertebral artery with stenosis and three kinds of stents with different types of links (they were named as L-stent, V-stent and S-stent, respectively, according to the shape of links) were constructed by using Pro/Engineering. Based on the simulation results of the expansion of these stents in the stenotic vertebral artery, three finite element models of the stented vertebral artery were established for fluid flow analysis. Hemodynamic simulation was performed for the three models using ANSYS-CFX. Results: Compared with V-link and S-link stent, L-link stent caused smaller area of low wall shear stress distributions and smaller blood stagnation area. Conclusions: With better hemodynamic effect, L-stent can potentially reduce the possibility of in-stent restenosis and provide scientific references for the choice of stent, the design of stent structure and surgical planning of stent intervention.

关键词:

Arterial stenosis; Computational fluid dynamics; Endovascular stent; Hemodynamics; Numerical simulation

作者机构:

  • [ 1 ] [Zhang, Z.-Z.]College of Life Science and Bio-engineering, Beijing University of Technology, Beijing 100124, China
  • [ 2 ] [Qiao, A.-K.]College of Life Science and Bio-engineering, Beijing University of Technology, Beijing 100124, China
  • [ 3 ] [Fu, W.-Y.]College of Life Science and Bio-engineering, Beijing University of Technology, Beijing 100124, China
  • [ 4 ] [Fu, W.-Y.]College of Architecture and Civil Engineering, Beijing University of Technology, Beijing 100124, China
  • [ 5 ] [Fu, W.-Y.]College of Mechanical and Electrical Engineering, Beijing Union University, Beijing 100020, China

通讯作者信息:

  • 乔爱科

    [Qiao, A.-K.]College of Life Science and Bio-engineering, Beijing University of Technology, Beijing 100124, China

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来源 :

Journal of Medical Biomechanics

ISSN: 1004-7220

年份: 2013

期: 2

卷: 28

页码: 148-153

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