收录:
摘要:
It is highly desirable and a great challenge for red light emission of carbon dots under long wavelength excitation. Here, we developed a facile route to synthesize carbon dots with red emission due to the doping effect of S and N elements, borrowing from the concept of the semiconductor. The maximum emission locates at 594 nm under 560 nm excitation. The absolute photoluminescence (PL) quantum yield (QY) is as high as 29% and 22% in ethanol and water, respectively. XPS and FTIR spectra illustrated that there exist -SCN and -COOH groups on the surface of the carbon dots. They endow the carbon dots with high sensitivity for ion detection of Fe3+. The quenched PL emission of Fe3+-S,N-CDs can be recovered by adding ascorbic acid to release the -COOH and -SCN group due to Fe2+ formation in the presence of ascorbic acid. High PL QY of red emission is beneficial to application in bioimaging. Doxorubicin was loaded onto carbon dots through pi-pi stacking to form a theranostic agent. When the CD-Dox was injected into the tumor site, a strong PL emission was observed. The PL intensity indicates the concentration of the theranostic agent. After 7 times injection, both the tumor size and weight clearly decrease. The results demonstrate that the S,N-CDs are a potentially excellent bioimaging component in the theranostic field.
关键词:
通讯作者信息:
电子邮件地址:
来源 :
ACS APPLIED MATERIALS & INTERFACES
ISSN: 1944-8244
年份: 2017
期: 22
卷: 9
页码: 18549-18556
9 . 5 0 0
JCR@2022
ESI学科: MATERIALS SCIENCE;
ESI高被引阀值:287
中科院分区:2