Accurate　implantation　of　pedicle　screw　in　spinal　deformity　correction　surgeries　is　always　challenging.　We　have　developed　a　method　of　pedicle　screw　placement　in　severe　and　rigid　scoliosis　with　a　multi-level　3D　printing　drill　guide　template.　From　November　2011　to　March　2015,　ten　patients　(4　males　and　6　females)　with　severe　and　rigid　scoliosis　(Cobb　angle　＞　70A　degrees　and　flexibility　＜　30%)were　included.　Multi-level　template　was　designed　and　manufactured　according　to　the　part　(two　or　three　levels)　of　the　most　severe　deformity.　The　drill　template　was　then　placed　on　the　corresponding　vertebral　surface.　Then,　pedicle　screws　were　carefully　inserted　along　the　trajectories.　The　other　screws　were　placed　in　free　hand.　After　surgery,　the　positions　of　the　pedicle　screws　were　evaluated　by　CT　scan　and　graded　for　validation.　48　screws　were　implanted　using　templates,　other　104　screws　in　free　hand,　and　the　accuracies　were　93.8　and　78.8%,　respectively,　with　significant　difference.　The　deformity　correction　ratio　was　67.1　and　41.2%　in　coronal　and　sagittal　plane　post-operatively,　respectively.　The　average　operation　time　was　234.0　+/-　34.1　min,　and　average　blood　loss　was　557　+/-　67.4　ml.　With　the　application　of　multi-level　template,　the　incidence　of　cortex　perforation　in　severe　and　rigid　scoliosis　decreased　and　this　technology　is,　therefore,　potentially　applicable　in　clinical　practice.