In　this　paper,　the　influence　of　morphology　of　coronary　artery　stenosis　on　fractional　flow　reserve　(FFR)　was　investigated.　The　stenosis　ratio,　length,　number,　arc,　and　offset　were　included　in　the　morphology　of　coronary　artery　stenosis.　Different　idealized　models　of　coronary　artery　stenosis　based　on　clinical　data　were　established　in　Pro/Engineering.　Numerical　simulations　were　carried　out　to　analyze　the　hemodynamic　parameters　of　the　models.　A　steady　blood　flow　velocity　was　assigned　at　the　inlet.　A　constant　pressure　was　assigned　at　the　outlet.　The　CFX　finite　element　numerical　simulation　was　used　to　calculate　the　models.　Then　the　pressure　value　at　the　distal　end　and　proximal　end　of　the　stenosis　was　extracted　for　FFR　analysis.　The　influence　of　factors　on　FFR　was　investigated　by　analyzing　each　factors　and　their　corresponding　fractional　flow　reserve.　The　stenosis　is　more　likely　to　cause　myocardial　ischemia　when　the　stenosis　has　larger　ratio,　longer　size,　more　number,　more　irregular　shape　and　bigger　offset.　Among　the　factors,　the　stenosis　ratio　and　length　affect　the　FFR　value　more　strongly.　It　will　be　likely　to　cause　FFR　less　than　0.　80　and　lead　to　myocardial　ischemia　when　the　stenosis　ratio　surpasses　70%,　the　number　of　stenosis　is　more　than　two　with　irregular　shapes.　The　stenosis　ratio,　length,　number,　stenosis　arc,　and　the　stenosis　offset　have　significant　effect　on　FFR　where　the　stenosis　ratio　and　the　number　of　stenosis　have　the　most　significant　influence,　while　the　distance　between　adjacent　stenosis　has　little　influence　on　FFR.