The　application　of　microbubble　technology　for　ozonation　wastewater　treatment　could　enhance　ozone　mass　transfer,　improve　ozonation　performance　and　increase　ozone　utilization　efficiency.　The　ozone　microbubbles　were　used　to　treat　synthetic　acid　red　3R　wastewater　in　the　present　study,　and　compared　to　ozone　conventional　bubbles.　The　ozone　mass　transfer　and　ozonation　characteristics　of　acid　red　3R　were　investigated　when　ozone　microbubbles　and　ozone　conventional　bubbles　were　applied.　The　results　confirmed　the　enhanced　ozone　mass　transfer　using　microbubbles.　The　ozone　mass　transfer　coefficient　using　microbubbles　was　3.6　times　higher　than　that　using　conventional　bubbles　under　the　same　conditions.　Simultaneously,　the　ozone　decomposition　coefficient　using　microbubbles　was　6.2　times　higher　than　that　using　conventional　bubbles,　which　would　be　favorable　for　·OH　generation.　The　ozonation　rate　and　mineralization　efficiency　of　acid　red　3R　could　be　improved　significantly　using　ozone　microbubbles.　A　TOC　removal　efficiency　of　78.0%　was　achieved　using　ozone　microbubbles,　which　was　about　2　times　higher　than　that　using　ozone　conventional　bubbles.　The　ozone　utilization　efficiency　using　microbubbles　was　much　higher　that　using　conventional　bubbles　during　ozonation　treatment　of　acid　red　3R.　The　average　ozone　utilization　efficiencies　were　97.8%　and　69.3%　when　microbubbles　and　conventional　bubbles　were　used,　respectively.　The　oxidative　ability　of　ozone　microbubbles　could　be　increased　by　enhancing　·OH　generation,　and　as　a　result,　the　oxidative　reaction　of　degradation　intermediates　was　accelerated　by　ozone　microbubbles.　Especially,　the　mineralization　ability　of　small　organic　acid　intermediates　using　ozone　microbubbles　was　about　1.6　times　higher　than　that　using　ozone　conventional　bubbles.　©,　2015,　Science　Press.　All　right　reserved.