In　nature,　microorganisms　tend　to　form　biofilms　that　consist　of　extracellular　polymeric　substances　with　embedded　sessile　cells.　Biofilms,　especially　mixed-culture　synergistic　biofilm　consortia,　are　notoriously　difficult　to　treat.　They　employ　various　defense　mechanisms　against　attacks　from　antimicrobial　agents.　Problematic　industrial　biofilms　cause　biofouling　as　well　as　biocorrosion,　also　known　as　microbiologically　influenced　corrosion.　Biocides　are　often　used　to　treat　biofilms　together　with　scrubbing　or　pigging.　Unfortunately,　chemical　treatments　suppress　vulnerable　microbial　species　while　allowing　resistant　species　to　take　over.　Repeated　treatment　cycles　are　typically　needed　in　biofilm　mitigation.　This　leads　to　biocide　dosage　escalation,　causing　environmental　problems,　higher　costs　and　sometimes　operational　problems　such　as　scale　formation.　New　treatment　methods　are　being　developed　such　as　enhanced　biocide　treatment　and　bacteriophage　treatment.　Special　materials　such　as　antibacterial　stainless　steels　are　also　being　created　to　combat　biofilms.　This　review　discussed　some　of　the　advances　made　in　the　fight　against　problematic　industrial　biofilms.