Three-dimensionally　ordered　macroporous　La0.6Sr0.4CoO3　(3DOM　LSCO)　and　its　supported　gold　and　manganese　oxide　(yMn(3)O(4)-zAu/3DOM　LSCO;　y　=0.75-2.50　wt%,　z　=　ca.　2.0　wt%)　nanoparticles　(NPs)　were　prepared　using　the　polymethyl　methacrylate-templating,　polyvinyl　alcohol-protected　reduction,　and　physical　adsorption　methods,　respectively.　Physicochemical　properties　of　the　samples　were　characterized　by　means　of　numerous　techniques,　and　their　catalytic　activities　were　evaluated　for　the　oxidation　of　toluene.　It　is　shown　that　the　3DOM　LSCO　in　yMn(3)O(4)-zAu/3DOM　LSCO　with　a　surface　area　of　20-24　m(2)/g　displayed　a　rhombohedral　crystal　structure,　and　Mn3O4　(size:　5-12　nm)　and　Au　(size:　3-4　nm)　NPs　were　highly　dispersed　on　the　surface　of　3DOM　LSCO.　There　were　good　correlations　of　adsorbed　oxygen　species　concentration　and　low-temperature　reducibility　with　catalytic　activity　of　the　sample.　The　1.67Mn(3)O(4)-2Au/3DOM　LSCO　sample　performed　the　best,　giving　the　T-50%　and　T-90%　(temperatures　required　for　achieving　toluene　conversions　of　50　and　90%)　of　214　and　230　degrees　C　at　a　space　velocity　of　20,000　mL/(gh),　respectively.　The　introduction　of　water　vapor　to　the　reaction　system　caused　a　partial　deactivation　of　the　1.67Mn(3)O(4)-2Au/3DOM　LSCO　sample,　and　such　a　deactivation　was　reversible.　The　apparent　activation　energies　(41.7-47.4　kJ/mol)　obtained　over　yMn(3)O(4)-2Au/3DOM　LSCO　were　lower　than　those　(49.2-56.81KJ/mol)　obtained　over　3DOM　LSCO,　2Au/3DOM　LSCO,　and　1.56Mn(3)O(4)-2Au/Bulk　LSCO.　It　is　concluded　that　the　large　surface　area,　high　adsorbed　oxygen　species　concentration,　good　low-temperature　reducibility,　and　strong　interaction　between　Au　or　Mn3O4　NPs　and　3DOM　LSCO　were　responsible　for　the　good　catalytic　performance　of　1.67Mn(3)O(4)-2Au/3DOM　LSCO.　(C)　2016　Elsevier　B.V.　All　rights　reserved.