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学者姓名：张楠
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摘要 ：
Debate and scientific inquiries regarding airborne transmission of respiratory infections such as COVID-19 and influenza continue. Health authorities including the WHO and the US CDC have recognized the airborne transmission of COVID-19 in specific settings, although the ventilation requirements remain to be determined. In this work we consider the long-range airborne transmission as an extended short-range airborne route, which reconciles the link between short- and long-range airborne routes. The effective short-range distance is defined as the distance in short range at which long-range route has the same volumetric exposure value as that due to short-range route. Our data show that a decrease in ventilation rate or room volume per person, or an increase in the ratio of the number of infected to susceptible people reduces the effective short-range distance. In a normal breathing scenario with one out of five people infected and a room volume of 12 m3 per person to ensure an effective short-range distance of 1.5 m, a ventilation rate of 10 L/s per person is needed for a duration of 2 h. Our results suggest that effective environmental prevention strategies for respiratory infections require appropriate increases in the ventilation rate while maintaining a sufficiently low occupancy. Practical implications: Demonstration of the long-range airborne route as an extended short-range airborne route suggests the significant role played by building ventilation in respiratory infection exposure. The reconciliation of short- and long-range airborne transmission suggests that the commonly observed dominance of close-contact transmission is a probable evidence of short-range airborne transmission, following a separate earlier study that revealed the relative insignificance of large droplet transmission in comparison with the short-range airborneroute. Existing ventilation standards do not account for respiratory infection control, and this study presents a possible approach to account for infection under new ventilation standards.
关键词 ：
Airborne transmission Airborne transmission COVID-19 COVID-19 Crowding Crowding Indoor environment Indoor environment Ventilation rate Ventilation rate
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| GB/T 7714 | Chen, Wenzhao , Qian, Hua , Zhang, Nan et al. Extended short-range airborne transmission of respiratory infections [J]. | JOURNAL OF HAZARDOUS MATERIALS , 2022 , 422 . |
| MLA | Chen, Wenzhao et al. "Extended short-range airborne transmission of respiratory infections" . | JOURNAL OF HAZARDOUS MATERIALS 422 (2022) . |
| APA | Chen, Wenzhao , Qian, Hua , Zhang, Nan , Liu, Fan , Liu, Li , Li, Yuguo . Extended short-range airborne transmission of respiratory infections . | JOURNAL OF HAZARDOUS MATERIALS , 2022 , 422 . |
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摘要 ：
通过构建数学模型,定量研究了1个3人家庭环境中飞沫传播、接触传播和气溶胶传播在COVID-19传播中的作用。研究表明,飞沫传播和接触传播在COVID-19传播中起着最重要的作用。和患者交流时保持1.5～2 m的空间距离对控制飞沫传播至关重要,洗手和保护环境表面清洁是控制接触传播的最有效手段。虽然通过气溶胶途径传播风险相对较小,但当患者呼出飞沫中病原体浓度较高时(患者可能为超级感染者),在家庭环境中24 h暴露下,气溶胶传播风险依然可以高达26%。
关键词 ：
接触传播 接触传播 数学模型 数学模型 新型冠状病毒 新型冠状病毒 气溶胶传播 气溶胶传播 相对重要性 相对重要性 飞沫传播 飞沫传播
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| GB/T 7714 | 雷浩 , 肖胜蓝 , 张楠 et al. 新型冠状病毒在家庭环境中的主要传播途径 [J]. | 科技导报 , 2021 , 39 (09) : 78-86 . |
| MLA | 雷浩 et al. "新型冠状病毒在家庭环境中的主要传播途径" . | 科技导报 39 . 09 (2021) : 78-86 . |
| APA | 雷浩 , 肖胜蓝 , 张楠 , 魏健健 , 金滔 . 新型冠状病毒在家庭环境中的主要传播途径 . | 科技导报 , 2021 , 39 (09) , 78-86 . |
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摘要 ：
Following advancement in urbanization, outdoor thermal comfort is receiving increasing attention, with radiation being an influencing factor. To determine the shading preference, instead of a subjective questionnaire survey, an objective foot vote approach was proposed using remote sensing images. Subsequently, the meteorological data of cities were obtained from the Bureau of Meteorology. From the results, the foot vote was approximately consistent with the PMV, and pedestrians tended to move to the shaded area if it was hot and to the non-shaded area if it was cold. However, people do not move if the foot vote value ranges from 1 to 2, and the thermal acceptance range of PET is 19.2–29 °C in Beijing when using the definitions of foot vote. The outdoor thermal acceptance differs significantly with the types of outdoor sites and climates, and pedestrians in Beijing are significantly more sensitive than those in Wuhan if the outdoor thermal environment changes. Compared to transportation hubs and shopping malls, pedestrians in public buildings are less sensitive, whereas those in scenic spots are more sensitive. Results from this study will be beneficial to policymakers in urban designing to renovate and improve thermally comfortable urban environments at the pedestrian level. © 2021 Elsevier Ltd
关键词 ：
Meteorology Meteorology Remote sensing Remote sensing Surveys Surveys Thermal comfort Thermal comfort
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| GB/T 7714 | Xue, Peng , Jia, Xiaoyu , Lai, Dayi et al. Investigation of outdoor pedestrian shading preference under several thermal environment using remote sensing images [J]. | Building and Environment , 2021 , 200 . |
| MLA | Xue, Peng et al. "Investigation of outdoor pedestrian shading preference under several thermal environment using remote sensing images" . | Building and Environment 200 (2021) . |
| APA | Xue, Peng , Jia, Xiaoyu , Lai, Dayi , Zhang, Xiaojing , Fan, Cheng , Zhang, Weirong et al. Investigation of outdoor pedestrian shading preference under several thermal environment using remote sensing images . | Building and Environment , 2021 , 200 . |
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摘要 ：
By the end of February 2021, COVID-19 had spread to over 230 countries, with more than 100 million confirmed cases and 2.5 million deaths. To control infection spread with the least disruption to economic and societal activities, it is crucial to implement the various interventions effectively. In this study, we developed an agentbased SEIR model, using real demographic and geographic data from Hong Kong, to analyse the efficiency of various intervention strategies in preventing infection by the SARS-CoV-2 virus. Close contact route including short-range airborne is considered as the main transmission routes for COVID-19 spread. Contact tracing is not that useful if all other interventions have been fully deployed. The number of infected individuals could be halved if people reduced their close contact rate by 25%. For reducing transmission, students should be prioritized for vaccination rather than retired older people and preschool aged children. Home isolation, and taking the nucleic acid test (NAT) as soon as possible after symptom onset, are much more effective interventions than wearing masks in public places. Temperature screening in public places only disrupted the infection spread by a small amount when other interventions have been fully implemented. Our results may be useful for other highly populated cities, when choosing their intervention strategies to prevent outbreaks of COVID-19 and similar diseases.
关键词 ：
Close contact Close contact COVID-19 COVID-19 Mask Mask SEIR model SEIR model Temperature screening Temperature screening Vaccine Vaccine
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| GB/T 7714 | Zhang, Nan , Chan, Pak-To Jack , Jia, Wei et al. Analysis of efficacy of intervention strategies for COVID-19 transmission: A case study of Hong Kong [J]. | ENVIRONMENT INTERNATIONAL , 2021 , 156 . |
| MLA | Zhang, Nan et al. "Analysis of efficacy of intervention strategies for COVID-19 transmission: A case study of Hong Kong" . | ENVIRONMENT INTERNATIONAL 156 (2021) . |
| APA | Zhang, Nan , Chan, Pak-To Jack , Jia, Wei , Dung, Chung-Hin , Zhao, Pengcheng , Lei, Hao et al. Analysis of efficacy of intervention strategies for COVID-19 transmission: A case study of Hong Kong . | ENVIRONMENT INTERNATIONAL , 2021 , 156 . |
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摘要 ：
Fomites are known to spread infectious diseases, but their role in determining transmission risk remains unclear. The association of surface touch networks (STNs), proposed to explain this risk, with real-life surface contamination has not yet been demonstrated. To construct STNs, we collected surface touch data from 23 to 26 scholars through 2 independent experiments conducted in office spaces for 13 h each. In parallel, a tracer bacterium (Lactobacillus bulgaricus) was spread by a designated carrier in each experiment during normal activities; the subsequent extent of surface contamination was assessed using qPCR. The touch data were also analyzed using an agent-based model that predicted the observed contamination. Touching public (door handles) and hidden public (desks, chair seatbacks) surfaces that connected occupants, sparse hand-to-hand contact, and active carriers contributed significantly to contamination spread, which was also correlated with the size of the social group containing carriers. The natural and unsupervised experiments reflected realistic exposure levels of mouths (1-10 ppm of total contamination spread by one root carrier), nostrils (-1 ppm), and eyes (-0.1 ppm). We conclude that the contamination degree of known and hidden public surfaces can indicate fomite exposure risk. The social group effect could trigger superspreading events through fomite transmission.
关键词 ：
Fomite exposure Fomite exposure Infection control Infection control Surface hygiene Surface hygiene Surface touch network Surface touch network Surrogate tracer Surrogate tracer
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| GB/T 7714 | Wang, Peihua , Zhang, Nan , Miao, Te et al. Surface touch network structure determines bacterial contamination spread on surfaces and occupant exposure [J]. | JOURNAL OF HAZARDOUS MATERIALS , 2021 , 416 . |
| MLA | Wang, Peihua et al. "Surface touch network structure determines bacterial contamination spread on surfaces and occupant exposure" . | JOURNAL OF HAZARDOUS MATERIALS 416 (2021) . |
| APA | Wang, Peihua , Zhang, Nan , Miao, Te , Chan, Jack P. T. , Huang, Hong , Lee, Patrick K. H. et al. Surface touch network structure determines bacterial contamination spread on surfaces and occupant exposure . | JOURNAL OF HAZARDOUS MATERIALS , 2021 , 416 . |
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摘要 ：
Background: Coronavirus disease 2019 (COVID-19) is primarily a respiratory disease that has become a global pandemic. Close contact plays an important role in infection spread, while fomite may also be a possible transmission route. Research during the COVID-19 pandemic has identified long-range airborne transmission as one of the important transmission routes although lack solid evidence. Methods: We examined video data related to a restaurant associated COVID-19 outbreak in Guangzhou. We observed more than 40,000 surface touches and 13,00 0 episodes of close contacts in the restaurant during the entire lunch duration. These data allowed us to analyse infection risk via both the fomite and close contact routes. Results: There is no significant correlation between the infection risk via both fomite and close contact routes among those who were not family members of the index case. We can thus rule out virus transmission via fomite contact and interpersonal close contact routes in the Guangzhou restaurant outbreak. The absence of a fomite route agrees with the COVID-19 literature. Conclusions: These results provide indirect evidence for the long-range airborne route dominating SARSCoV-2 transmission in the restaurant. We note that the restaurant was poorly ventilated, allowing for increasing airborne SARS-CoV-2 concentration. (C) 2021 The British Infection Association. Published by Elsevier Ltd. All rights reserved.
关键词 ：
Airborne Airborne Close contact Close contact Covid-19 Covid-19 Fomite Fomite Human behavior Human behavior
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| GB/T 7714 | Zhang, Nan , Chen, Xuguang , Jia, Wei et al. Y Evidence for lack of transmission by close contact and surface touch in a restaurant outbreak of COVID-19 [J]. | JOURNAL OF INFECTION , 2021 , 83 (2) : 207-216 . |
| MLA | Zhang, Nan et al. "Y Evidence for lack of transmission by close contact and surface touch in a restaurant outbreak of COVID-19" . | JOURNAL OF INFECTION 83 . 2 (2021) : 207-216 . |
| APA | Zhang, Nan , Chen, Xuguang , Jia, Wei , Jin, Tianyi , Xiao, Shenglan , Chen, Wenzhao et al. Y Evidence for lack of transmission by close contact and surface touch in a restaurant outbreak of COVID-19 . | JOURNAL OF INFECTION , 2021 , 83 (2) , 207-216 . |
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摘要 ：
Fomites can transmit some infectious diseases. Human touch behaviors are known to affect virus transmission in buildings. Using video cameras in a graduate student office, we collected more than 98,000 touch actions from 14 h of high-resolution video data of surfaces touched by fingers, palms, and backs of hands. Based on the collected data, we simulated infection spread via the fomite route. 90% of touches to mucous membranes are by fingers (70% by fingers of the nondominant hand; 20% by fingers of the dominant hand). 3% of the virus released into the atmosphere by those infected was transmitted to other students' hands, personal-use surfaces, and public surfaces. Public surfaces are responsible for 53% of virus transmission due to surface touch to susceptible students. 65% of the virus transmitted to the mucous membranes, is by nondominant hands. 93% of virus intake via mucous membranes of the susceptible was from fingers. Door handles and mobile phones transferred the most viral loads to hands of the susceptible. Total virus exposure due to touching has no significant relationship with the duration of being indoors, but human behavior does. Behavior-related intervention strategies are much more efficient than other strategies such as public surface disinfection. If we never touch other's personal surfaces, we would reduce our exposure to the virus by 80%.
关键词 ：
Fomite Fomite Human behavior Human behavior Infection spread Infection spread Mucous membrane Mucous membrane Pathogen Pathogen Public surface Public surface
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| GB/T 7714 | Zhang, Nan , Wang, Peihua , Miao, Te et al. Real human surface touch behavior based quantitative analysis on infection spread via fomite route in an office [J]. | BUILDING AND ENVIRONMENT , 2021 , 191 . |
| MLA | Zhang, Nan et al. "Real human surface touch behavior based quantitative analysis on infection spread via fomite route in an office" . | BUILDING AND ENVIRONMENT 191 (2021) . |
| APA | Zhang, Nan , Wang, Peihua , Miao, Te , Chan, Pak-To , Jia, Wei , Zhao, Pengcheng et al. Real human surface touch behavior based quantitative analysis on infection spread via fomite route in an office . | BUILDING AND ENVIRONMENT , 2021 , 191 . |
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摘要 ：
Background: School closure is a common mitigation strategy during severe influenza epidemics and pandemics. However, the effectiveness of this strategy remains controversial. In this study, we aimed to explore the effectiveness of school closure on seasonal influenza epidemics in provincial-level administrative divisions (PLADs) with varying urbanization rates in China. Methods: This study analyzed influenza surveillance data between 2010 and 2019 provided by the Chinese National Influenza Center. Taking into consideration the climate, this study included a region with 3 adjacent PLADs in Northern China and another region with 4 adjacent PLADs in Southern China. The effect of school closure on influenza transmission was evaluated by the reduction of the effective reproductive number of seasonal influenza during school winter breaks compared with that before school winter breaks. An age-structured Susceptible-Infected-Recovered-Susceptible (SIRS) model was built to model influenza transmission in different levels of urbanization. Parameters were determined using the surveillance data via robust Bayesian method. Results: Between 2010 and 2019, in the less urbanized provinces: Hebei, Zhejiang, Jiangsu and Anhui, during school winter breaks, the effective reproductive number of seasonal influenza epidemics reduced 14.6% [95% confidential interval (CI): 6.2-22.9%], 9.6% (95% CI: 2.5-16.6%), 7.3% (95% CI: 0.1-14.4%) and 8.2% (95% CI: 1.1-15.3%) respectively. However, in the highly urbanized cities: Beijing, Tianjin and Shanghai, it reduced only 5.2% (95% CI: -0.7-11.2%), 4.1% (95% CI: -0.9-9.1%) and 3.9% (95% CI: -1.6-9.4%) respectively. In China, urbanization is associated with decreased proportion of children and increased social contact. According to the SIRS model, both factors could reduce the impact of school closure on seasonal influenza epidemics, and the proportion of children in the population is thought to be the dominant influencing factor. Conclusions: Effectiveness of school closure on the epidemics varies with the age structure in the population and social contact patterns. School closure should be recommended in the low urbanized regions in China in the influenza seasons.
关键词 ：
China China Contact Contact Influenza epidemics Influenza epidemics School closure School closure Urbanization Urbanization
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| GB/T 7714 | Lei, Hao , Jiang, Hangjin , Zhang, Nan et al. Increased urbanization reduced the effectiveness of school closures on seasonal influenza epidemics in China [J]. | INFECTIOUS DISEASES OF POVERTY , 2021 , 10 (1) . |
| MLA | Lei, Hao et al. "Increased urbanization reduced the effectiveness of school closures on seasonal influenza epidemics in China" . | INFECTIOUS DISEASES OF POVERTY 10 . 1 (2021) . |
| APA | Lei, Hao , Jiang, Hangjin , Zhang, Nan , Duan, Xiaoli , Chen, Tao , Yang, Lei et al. Increased urbanization reduced the effectiveness of school closures on seasonal influenza epidemics in China . | INFECTIOUS DISEASES OF POVERTY , 2021 , 10 (1) . |
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摘要 ：
Infectious disease-causing pathogens can be transmitted via contact with contaminated environmental surfaces (i.e., fomite transmission). However, the physical mechanism of fomite transmission remains unclear because of a lack of suitable surrogate tracers. In this study, the non-toxic, non-human-origin and gram-positive bacterium Lactobacillus delbrueckii subsp. Bulgaricus was selected as a tracer, and its applicability for studying bacterial contamination spread on environmental surfaces was investigated in an office setting. After bacterial introduction by a designated carrier, surface contamination levels indicated by the L. bulgaricus proline iminopeptidase (pepIP) gene copy numbers were quantified using an optimized qPCR assay. This qPCR assay exhibited a high sensitivity (55 copies per reaction mixture and 1585 copies per surface sample), a wide dynamic range (7 orders of magnitude) and a high specificity for pepIP gene in environmental surface samples. Three independent, natural and unsupervised field experiments involving human participants confirmed the applicability of L. bulgaricus as a tracer in field studies and the pepIP gene as a unique marker of externally introduced contamination. Experimentally, contamination was distributed nearly equally over public surfaces, the carrier's seat location and the other seat locations in the office setting. An analysis by seat location revealed that the contamination level was attenuated as the physical distance from the carrier's seat location increased. Volunteers' faces were ubiquitously contaminated, suggesting a potentially high risk of fomite exposure via mucous membranes. In conclusion, L. bulgaricus can feasibly be used as a tracer organism in future large-scale field studies of bacterial contamination spread on environmental surfaces. © 2021 Elsevier Ltd
关键词 ：
Bacteria Bacteria Contamination Contamination Genes Genes Location Location Optimization Optimization Polymerase chain reaction Polymerase chain reaction
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| GB/T 7714 | Wang, Peihua , Zhang, Nan , Lee, Patrick K.H. et al. Quantification of Lactobacillus delbrueckii subsp. Bulgaricus and its applicability as a tracer for studying contamination spread on environmental surfaces [J]. | Building and Environment , 2021 , 197 . |
| MLA | Wang, Peihua et al. "Quantification of Lactobacillus delbrueckii subsp. Bulgaricus and its applicability as a tracer for studying contamination spread on environmental surfaces" . | Building and Environment 197 (2021) . |
| APA | Wang, Peihua , Zhang, Nan , Lee, Patrick K.H. , Li, Yuguo . Quantification of Lactobacillus delbrueckii subsp. Bulgaricus and its applicability as a tracer for studying contamination spread on environmental surfaces . | Building and Environment , 2021 , 197 . |
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摘要 ：
Personal protective behaviors and their dynamic change are known to play a major role in the community spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causal pathogen of the coronavirus disease 2019 (COVID-19) pandemic. In this study, a total of 3229 students in Chinese universities completed an online survey about their knowledge on transmission and personal protective behavior before and after COVID19 vaccination. Of the respondents, 87.6% had been vaccinated. Most students believed that the large droplet (97.0%) and short-range airborne (89.3%) routes were the two most likely SARS-CoV-2 transmission routes, whereas only 24.1% considered long-range airborne transmission to be possible. Students who would be expected to possess better knowledge about virus transmission (e.g., students of medicine) reported better personal protective behaviors. Female students reported relatively better personal hygiene practices than male students, so did the confident students than their diffident peers. Students washed their hands on average of 5.76 times per day during the pandemic. Students at universities in southern regions washed their hands more frequently but paid less attention to indoor ventilation than did their northern counterparts. Interestingly, students who are fear of being infected had the bad personal hygiene. University students wore 22% less masks in public indoor environments after vaccination. Chinese university students weakened their personal protective behavior after vaccination and it may increase the potential risk of infection in the new waves of variant virus (e.g. delta).
关键词 ：
COVID-19 COVID-19 Mask Mask Personal hygiene Personal hygiene Personal protective behavior Personal protective behavior University student University student Vaccination Vaccination
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| GB/T 7714 | Zhang, Nan , Liu, Xiyue , Jin, Tianyi et al. Weakening personal protective behavior by Chinese university students after COVID-19 vaccination [J]. | BUILDING AND ENVIRONMENT , 2021 , 206 . |
| MLA | Zhang, Nan et al. "Weakening personal protective behavior by Chinese university students after COVID-19 vaccination" . | BUILDING AND ENVIRONMENT 206 (2021) . |
| APA | Zhang, Nan , Liu, Xiyue , Jin, Tianyi , Zhao, Pengcheng , Miao, Doudou , Lei, Hao et al. Weakening personal protective behavior by Chinese university students after COVID-19 vaccination . | BUILDING AND ENVIRONMENT , 2021 , 206 . |
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